Pasgaard-Westerman rethinks the ontological and epistemological understanding of world, other and self by opposing the general anthropological paradigm within contemporary philosophy. Signs and interpretations are not functions of Man instead Man is conceived as certain “signo-interpretational” relations to world, other and self. Opposing more traditional hermeneutical approaches the signo-interpretational relations towards world, other and self are understood as a “skeptical disposition”. This skeptical disposition undercuts usual epistemological problems of skepticism and instead designates the permanent incompleteness of the process of interpretation and formulates an ethical imperative. This ethical imperative aims at an active dissolution of fixed signs an openness towards other signs and the holding back of definite interpretations. The book discusses how world appear as a sign-world, how the other appear within interpretational patterns, and how our signs of self are experienced. Discussing a wide range of epistemological and ontological questions and taking into account the perspectives of a broad range of philosophical traditions, a signo-interpretational account of reality, world-versions, other persons and self is presented.